我自己睇返暗瘡膏張紙，佢咁寫：There have been rare reports of birth defects among babies born to exposed to topical retinoids during pregnancy. However, there are no well controlled prospective studies of the use of topical retinoids, including adapalene, in pregnant women. A retrospective study of mother exposed to topical tretinoin during the first trimester of pregnancy found no increase in the incidence of birth defects.
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